Monograph Details
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Infections & Infestations
> Bacterial infections
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BICILLIN C-R |
| Manufacturer |
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King Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Penicillinase-sensitive penicillin. |
| Generic Name |
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Penicillin G benzathine, penicillin G procaine equal amounts; combined penicillin G dose 600,000Units/mL; susp for deep IM inj; contains parabens. |
| Also |
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• BICILLIN C-R 900/300
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| Indications |
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Susceptible moderately severe infections including respiratory, skin and soft tissue, erysipelas, scarlet fever, otitis media. |
| Adults and Children |
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C-R: Give by deep IM inj (buttock or, in young children, may give in anterolateral thigh). Group A strep: <30lbs: 600,000 units; 30–60lbs: 900,000–1.2 million units; > 60lbs: 2.4 million units; all as single dose (may split injections) or may give one-half total dose on day 1 and one-half on day 3. Pneumococcal (except meningitis) children: 600,000 units; adults 1.2 million units; give every 2–3 days until afebrile for 48 hrs. |
| Contraindications |
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Avoid intraarterial, intravascular, and intraneural inj. |
| Precautions |
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Cephalosporin, imipenem, or other allergy: not recommended. Asthma. Monitor renal and hematopoietic function in prolonged use. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Potentiated by probenecid. May cause false (+) glucose test with Clinitest. |
| Adverse Reactions |
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Rash, drug fever, serum sickness, anaphylaxis, blood dyscrasias, neuropathy, nephropathy, inj site reactions. |
| How Supplied |
C–R Tubex 600,000 units/mL (1mL, 2mL)—10 (w. 1 inch or 1.25 inch needles)
C–R disposable syringe 600,000 units/mL (4mL)—10 (w. 2 inch needles)
C–R 900/300 Tubex 1.2 million units/syringe (2mL)—10 (w. 1 inch or 1.25 inch needles) |
| Additional Resources |
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• Related Prescribing Note |
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