Monograph Details

Immune System > Immunization
TETANUS TOXOID BOOSTER
Manufacturer
Sanofi Pasteur, Inc.
Legal Classification
Rx
Pharmacological Class
Tetanus vaccine.
Generic Name
Tetanus toxoid booster vaccine; for IM or SC inj; contains thimerosal.
Indications
Tetanus immunization booster.
Adults and Children
<7yrs: not recommended. Give IM or SC in lateral mid-thigh or deltoid. ≥7yrs: After completion of primary immunization: 0.5mL every 10 years. Tetanus prophylaxis: see literature.
Contraindications
Not for primary immunization. History of systemic allergic or neurologic reactions to a previous dose of DT.
Precautions
Latex allergy. Previous arthus-type hypersensitivity reaction: do not give more frequently than every 10 years. Defer in moderate or severe active respiratory or other febrile infection (may vaccinate if mild or minor illness) or during polio outbreak. Bleeding disorders (use SC route). Immunosuppressed. History of Guillain-Barre syndrome within 6 weeks of last tetanus vaccine. Have epinephrine (1:1000) available. Elderly. Pregnancy (Cat.C). Nursing mothers.
Interactions
May get suboptimal response with immunosuppressants (eg, chemotherapy, high dose corticosteroids ≥2 weeks, radiation); consider deferring.
Adverse Reactions
Local reactions (eg, erythema, tenderness), malaise, fever, hypotension, pain, nausea, arthralgia; rare: neurological disorders.
How Supplied
Vial (7.5mL)—1
Additional Resources
Related Prescribing Note