Monograph Details
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Immune System
> Immunization
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PREVNAR |
| Manufacturer |
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Wyeth Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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PCV. |
| Generic Name |
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Pneumococcal 7-valent conjugate vaccine (diphtheria CRM197 protein) 16micrograms of saccharides per 0.5mL; susp for IM inj; preservative-free; contains aluminum. |
| Indications |
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Immunization of infants and toddlers against invasive disease and otitis media caused by S. pneumoniae due to serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. |
| Children |
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Each dose is 0.5mL IM into the anterolateral thigh for infants or the deltoid muscle for toddlers and children; avoid nerves and blood vessels. May pretreat with antipyretic. <6weeks: not recommended. ≥6weeks: 4 doses usually given at 2, 4, 6, and 12–15 months of age (may start at 6 weeks of age: give 1st three doses 4–8 weeks apart, and 4th dose at least 2 months after 3rd dose). Previously unvaccinated older infants and children: 7–11months of age: 3 doses (2nd dose at least 4 weeks after 1st dose, 3rd dose after 1st birthday and at least 2 months after 2nd dose); 12–23months of age: 2 doses at least 2 months apart; 2–9yrs of age: 1 dose once. |
| Adults |
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Not recommended. |
| Precautions |
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May defer in acute moderate or severe febrile illness. Immunocompromised: may get suboptimal response. Not a substitute for diphtheria, or for 23-valent polysaccharide pneumococcal vaccinations. Coagulation disorders. Have epinephrine inj available. Latex allergy. Pregnancy (Cat.C), nursing mothers: not recommended. |
| Interactions |
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Immunosuppressants: may get suboptimal response. |
| Adverse Reactions |
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Inj site reactions, irritability, drowsiness, fever, restless sleep, decreased appetite, vomiting, diarrhea, rash, hives. |
| How Supplied |
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Single-dose vials—5 |
| Additional Resources |
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• Related Prescribing Note |
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