Monograph Details
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Immune System
> Immunization
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M-M-R II |
| Manufacturer |
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Merck & Co., Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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MMR. |
| Generic Name |
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Measles, mumps and rubella viruses live, attenuated; for SC inj; contains neomycin, human albumin; preservative-free. |
| Indications |
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Measles, mumps and rubella immunization. A 2nd dose of measles vaccine is recommended. |
| Adults and Children |
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<12 months: usually not recommended. Each dose is 0.5mL. Give by SC inj into upper outer arm. First dose at 12–15 months of age, second dose at 4–6 years of age (ACIP recommendations). |
| Contraindications |
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Egg, gelatin, or neomycin hypersensitivity. Active respiratory or other febrile infection. Active untreated tuberculosis. Immunosuppression. Blood dyscrasias. Bone marrow or lymphatic malignancy. Pregnancy (Cat.C) during and for 3 months after vaccination. |
| Precautions |
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Have epinephrine inj available. History of febrile convulsions or cerebral injury. Defer vaccination for at least 3 months after blood or plasma transfusions or immune serum globulin, and for at least 1 month before or after other live virus vaccines (except oral polio). Nursing mothers: not recommended. |
| Interactions |
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Immunosuppressants (see Contraindications). May interfere with tuberculin test. |
| Adverse Reactions |
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Fever, rash, malaise, sore throat, headache, local reactions, arthritic symptoms, parotitis, orchitis, thrombocytopenia, purpura; encephalitis (rare). |
| How Supplied |
Single dose vial—1, 10 (w. diluent)
Multi-dose vial—1 (w. diluent) |
| Additional Resources |
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• Related Prescribing Note |
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