Monograph Details
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Immune System
> Immunization
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ENGERIX-B PEDIATRIC/ADOLESCENT |
| Manufacturer |
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GlaxoSmithKline Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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HB. |
| Generic Name |
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Hepatitis B vaccine (recombinant) 10micrograms/0.5mL; aluminum hydroxide adsorbed; IM inj; preservative-free; contains thimerosal (trace). |
| Also |
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• ENGERIX-B ADULT
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| Indications |
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Hepatitis B immunization. |
| Children |
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Give IM in anterolateral thigh or deltoid; see literature. Infants (mothers are HBsAG negative): 10micrograms at birth and repeat 1 and 6 months later; infants (mothers are HBsAG positive) and children through age 10yrs: 10micrograms at elected date and repeat 1 and 6 months later, or 10micrograms at elected date and repeat 1, 2, and 12 months later. High risk: consider hepatitis B immune globulin also. Booster doses: when appropriate, may use 10micrograms for children age 10yrs or younger, or 20micrograms for ages 11yrs and older. |
| Adults |
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Give IM in deltoid muscle. 11–19yrs: 10micrograms at elected date and repeat 1 and 6 months later, or 20micrograms at elected date and repeat 1, 2, and 12 months later, or 20micrograms at elected date and repeat 1 and 6 months later. >19yrs: 20micrograms at elected date and repeat 1 and 6 months later, or 20 micrograms at elected date and repeat 1, 2, and 12 months later. Hemodialysis: 40micrograms at elected date and repeat 1, 2, and 6 months later. High-risk: consider hepatitis B immune globulin also. Booster dose: when appropriate, may use 20micrograms for persons 11yrs of age and older; hemodialysis patients booster dose is 40micrograms. |
| Contraindications |
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Yeast hypersensitivity. |
| Precautions |
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May defer in acute febrile illness or active infection. May be given SC only if risk of hemorrhage. Have epinephrine inj available. Multiple sclerosis. Pregnancy (Cat.C). Nursing mothers. |
| Adverse Reactions |
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Local reactions, malaise, nausea, diarrhea, rash. Anaphylaxis. |
| How Supplied |
Pediatric/Adolescent (single-dose prefilled Tip-Lok syringe)—5 (without needles)
Pediatric/Adolescent (single-dose vials)—1, 10
Adult (single-dose prefilled Tip-Lok syringe)—5 (without needles)
Adult (single-dose vials)—1, 10, 25 |
| Additional Resources |
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• Related Prescribing Note |
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