Monograph Details
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Immune System
> Immunization
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ATTENUVAX |
| Manufacturer |
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Merck & Co., Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Measles vaccine. |
| Generic Name |
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Measles virus vaccine live; for SC inj after reconstitution; contains gelatin, sorbitol, neomycin, human albumin; preservative-free. |
| Indications |
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Measles immunization. |
| Adults and Children |
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Each dose is 0.5mL. Give by SC inj into upper outer arm. <12 months: not recommended. 12months: first dose at 12–15 months of age; revaccinate (may use MMR) at 4–6 years of age. |
| Contraindications |
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Defer in moderate or severe active respiratory or other febrile infection (may vaccinate if mild or minor illness). Active, untreated tuberculosis. Immunosuppressed (see literature). Blood dyscrasias. Bone marrow or lymphatic malignancy. Pregnancy (Cat.C) during; avoid pregnancy for 3 months after vaccination. |
| Precautions |
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Egg allergy. Thrombocytopenia. History of cerebral injury or convulsions. Defer vaccination for at least 3 months after blood or plasma transfusions or immune globulin, and for at least 1 month before or after other live virus vaccines (except Varivax and PedvaxHIB). Have epinephrine (1:1000) available. Elderly. Nursing mothers. |
| Interactions |
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Immunosuppressants. May interfere with tuberculin test. |
| Adverse Reactions |
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Local reactions, fever, syncope, headache, malaise, panniculitis, vasculitis, GI upset, thrombocytopenia, respiratory disorders, rash, otitis media, optic neuritis; encephalitis (rare). |
| How Supplied |
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Single-dose vials—1, 10 (w. diluent) |
| Additional Resources |
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• Related Prescribing Note |
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