Monograph Details
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Immune System
> Immunization
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ADACEL |
| Manufacturer |
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Sanofi Pasteur, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Vaccine (Tdap). |
| Generic Name |
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Tetanus and reduced diphtheria toxoids, acellular pertussis vaccine (aluminum phosphate adsorbed); susp for IM inj. |
| Indications |
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Diphtheria, tetanus, and pertussis booster immunization in persons 11–64 years of age. |
| Adults and Children |
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<11yrs or ≥65yrs: not recommended. 11–64yrs (≥5yrs after last dose of tetanus toxoid, diphtheria toxoid, and/or pertussis-containing vaccine): 0.5mL IM once into deltoid muscle. |
| Contraindications |
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Encephalopathy within 7 days after previous DTaP or DTwP vaccination, or life-threatening reaction to related vaccine. Progressive neurologic disorders. Uncontrolled epilepsy. Progressive encephalopathy. |
| Precautions |
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Fever (≥105 F within 48hrs), persistent inconsolable crying (≥3hrs within 48hrs), shock (within 48hrs), seizures (within 3 days), or Guillain-Barre syndrome (within 6 weeks) after previous DTaP or DTwP vaccine: see literature. Stable CNS disorders. Seizure risk. Acute illness. Immunosuppressed. Bleeding disorders. Have epinephrine (1:1000) available. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Concomitant vaccines: see literature. Immunosuppressants: may get suboptimal results. |
| Adverse Reactions |
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Local reactions, headache, fever, fatigue, arthralgia, GI upset. |
| Extra Text |
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Note: Register pregnant patients exposed to Adacel by calling (800) 822-2463. Report adverse events to VAERS by calling (800) 822-7967. Refer to www.cdc.gov for ACIP guidelines on vaccinating acutely ill patients. |
| How Supplied |
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Single-use vial—5, 10 |
| Additional Resources |
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• Related Prescribing Note |
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