Monograph Details
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Immune System
> Immunization
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ACTHIB |
| Manufacturer |
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Sanofi Pasteur, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Hib (PRP-T). |
| Generic Name |
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Haemophilus b conjugate 10micrograms (tetanus toxoid conjugate) per 0.5mL; pwd for IM inj after reconstitution with saline, Sanofi Pasteur DTaP, Tripedia. |
| Indications |
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Combined with supplied saline diluent by reconstitution: for the active immunization of children 2–18 months of age against H. influenzae type b. Combined with Tripedia (DTaP) vaccine by reconstitution: for the active immunization of children 15–18 months of age against H. influenzae type b, diphtheria, tetanus, and pertussis. |
| Children |
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Inject IM in thigh or deltoid. Reconstituted with DTaP, or saline: <2months: not recommended. As 1st, 2nd, 3rd dose in series: 0.5mL at 2, 4, and 6 months. Reconstituted with Tripedia (DTaP): <15months: not recommended. As 4th dose in series: 0.5mL at 15–18months, then 5th dose at 4–6yrs. Previously unvaccinated children: see literature. |
| Precautions |
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Immunodeficiency/ suppression, malignancies: may get suboptimal response. Delay administration in active infection or fever. Have epinephrine inj (1:1000) available. Protection begins 2 weeks after inoculation. Pregnancy (Cat.C): not recommended. |
| Adverse Reactions |
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Local pain, redness, swelling, irritability, drowsiness, anorexia, fever, GI upset. |
| Extra Text |
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Note: ActHIB may be reconstituted with either supplied saline diluent or Sanofi Pasteur DTaP, Tripedia. TriHIBit is a product of the reconstitution of ActHIB with Tripedia for the 4th dose only. |
| How Supplied |
Single-dose vials—5 (w. saline diluent)
Single-dose vials—5 (w. 5 Tripedia vials as diluent) |
| Additional Resources |
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• Related Prescribing Note |
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