Monograph Details
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Hematology
> Immune-mediated blood disorders
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RHOPHYLAC |
| Manufacturer |
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CSL Behring, LLC |
| Legal Classification |
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Rx
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| Generic Name |
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Rho (D) immune globulin human 1500 IU (300micrograms)/2mL; syringe; for IV or IM inj; preservative- and latex-free; contains albumin (human); solvent/detergent treated. |
| Indications |
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Suppression of Rh isoimmunization in non-sensitized Rho (D) negative women during pregnancy and in appropriate obstetrical conditions, unless the fetus or father is known to be Rho (D) negative. Suppression of Rh isoimmunization in Rho (D) negative individuals transfused with Rho (D) positive blood products. |
| Children |
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Not recommended. |
| Adults |
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See literature. Pregnancy (28–30 weeks gestation), postpartum prevention (within 72 hours), obstetric complications, invasive procedures during pregnancy: 1500 IU (300micrograms). Incompatible transfusions (within 72 hours): 100 IU (20micrograms) per 2mL transfused blood or per 1mL erythrocyte concentrate. |
| Contraindications |
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Rho (D) positive patients. IgA deficiency. |
| Precautions |
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Monitor patients 20 minutes after administration. Pregnancy (Cat.C). |
| Interactions |
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Do not give live vaccines within 3 months. |
| Adverse Reactions |
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Local or infusion reactions, fever, chills, headache; see literature. |
| How Supplied |
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Single-dose prefilled syringes—1, 10 |
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