Monograph Details
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Hematology
> Bleeding disorders
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THROMBIN-JMI |
| Manufacturer |
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King Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Topical hemostatic. |
| Generic Name |
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Thrombin [bovine origin] 5000 IU, 20000 IU; per vial; pwd for topical use after reconstitution; preservative-free. |
| Indications |
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Aid to hemostasis for oozing blood and minor bleeding from accessible capillaries and small venules. Adjunct for surgical hemostasis with absorbable gelatin sponge. |
| Children |
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Not recommended. |
| Adults |
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For topical use only. See literature. Profuse bleeding (eg, abraided surfaces of liver or spleen): 1000IU/mL. General use (eg. plastic surgery, dental extractions, skin grafting): 100IU/mL. May dilute to prepare intermediate strengths, if needed. Oozing surfaces: may use dry form. |
| Precautions |
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Not for injection or use in large blood vessels. Antibody formation: do not re-expose, abnormalities in hemostasis (eg, severe bleeding or thrombosis) more likely with repeated use. Pregnancy (Cat.C). Nursing mothers. |
| Adverse Reactions |
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Hypersensitivity reactions, antibody formation. |
| How Supplied |
Vials—1 (w. diluent)
Pump Spray Kit (20000 IU)—1 (w. diluent)
Syringe Spray Kit (20000 IU)—1 (w. diluent)
Epistaxis Kit (5000 IU)—1 (w. diluent) |
| Additional Resources |
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• Related Prescribing Note |
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