Monograph Details
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Hematology
> Anemias
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INFED |
| Manufacturer |
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Watson Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Hematinic. |
| Generic Name |
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Iron (as dextran complex) 50mg/mL; soln for IV or IM inj. |
| Indications |
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Iron deficiency where oral therapy is unsatisfactory or impossible. |
| Adults and Children |
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Give by IV or by deep IM (into upper outer quadrant of buttock only) inj. Administer 0.5mL test dose first. Iron deficiency anemia: determine total dose based on hemoglobin and body weight (see literature). Iron replacement for blood loss: Replacement iron (in mg) = blood loss (in mL) X hematocrit. Max daily doses: <5kg: 0.5mL (25mg), <10kg: 1mL (50mg), ≥10kg: 2mL (100mg). |
| Contraindications |
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Anemias not associated with iron deficiency. |
| Precautions |
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Severe hepatic impairment. Avoid during acute phase of infectious kidney disease. Dialysis. Avoid large IV doses: higher incidence of adverse events. Have epinephrine available. Cardiovascular disease. History of allergies, asthma. May reactivate quiescent rheumatoid arthritis. Neonates (avoid during first 4 months). Pregnancy (Cat. C). Nursing mothers. |
| Interactions |
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May falsely elevate serum bilirubin or decrease serum calcium levels. |
| Adverse Reactions |
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See literature. Anaphylactic reactions (may be fatal), cardiovascular events, pruritus, GI upset, arthralgia, arthritis, inj site reactions, others; possible IM inj site tumors, sepsis in neonates. |
| How Supplied |
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Vials (2mL)—10 |
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