Monograph Details

Gastrointestinal Tract > Nausea
BENADRYL INJECTION
Manufacturer
Pfizer Labs
Legal Classification
Rx
Pharmacological Class
Antihistamine.
Generic Name
Diphenhydramine HCl 50mg/mL; for IV or IM inj.
Indications
Motion sickness.
Children
Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.
Adults
10–50mg IV or deep IM; max 400mg/day.
Contraindications
Neonates. Premature infants. Nursing mothers.
Precautions
Asthma. Lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Children. Pregnancy (Cat.B).
Interactions
Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.
Adverse Reactions
Drowsiness, dizziness, anticholinergic effects, gastritis, paradoxical excitement, blood dyscrasias, hypotension.
How Supplied
Vial (10 mL)—1
Amp or syringe (1 mL)—10
Additional Resources
Related Prescribing Note