Monograph Details

Gastrointestinal Tract > Nausea
ALOXI CAPSULES
Manufacturer
Eisai Pharmaceuticals
Legal Classification
Rx
Pharmacological Class
Selective 5-HT3 receptor antagonist.
Generic Name
Palonosetron (as HCl) 0.5mg; caps.
Also
ALOXI
Indications
Prevention of acute nausea and vomiting due to initial and repeat courses of moderately emetogenic chemotherapy.
Children
<18yrs: not recommended.
Adults
≥18yrs: 0.5mg one hour prior to chemotherapy.
Precautions
Pregnancy (Cat.B). Labor & delivery. Nursing mothers: not recommended.
Adverse Reactions
Headache, constipation, fatigue, GI disturbances, dizziness, tachycardia, bradycardia, hypotension, QT prolongation.
How Supplied
Single-use vial (0.075mg/1.5mL)—5
(0.25mg/5mL)—1
Caps—5
Additional Resources
Related Prescribing Note