Monograph Details
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Gastrointestinal Tract
> Hyperacidity, GERD, and ulcers
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ROBINUL INJECTION |
| Manufacturer |
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Wyeth Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Anticholinergic. |
| Generic Name |
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Glycopyrrolate 0.2mg/mL; IM or IV inj; contains benzyl alcohol 0.9%. |
| Also |
• ROBINUL
• ROBINUL FORTE
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| Indications |
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Adjunct in peptic ulcer where oral therapy not tolerated. |
| Children |
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Not recommended. |
| Adults |
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0.1–0.2mg IV or IM every 4 hrs 1–4 times daily. |
| Contraindications |
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Glaucoma. Unstable cardiovascular status. Asthma. GI or urinary tract obstruction. Paralytic ileus or intestinal atony. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis. |
| Precautions |
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Reflux esophagitis. Autonomic neuropathy. Impaired hepatic or renal function. Cardiovascular disease. Tachycardia. Hypertension. Hyperthyroidism. High environmental temperature. Diarrhea. Elderly. Debilitated. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Concomitant antacids may inhibit absorption. Cyclopropane anesthetics may cause arrhythmias. Additive anticholinergic effects with other anticholinergics, narcotic analgesics, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics. |
| Adverse Reactions |
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Anticholinergic effects (e.g., dry mouth, blurred vision, constipation). |
| How Supplied |
Tabs—100
Inj (vials) Single dose 1mL—25
2mL—25
Multidose 5mL—25
20mL—1 |
| Additional Resources |
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• Related Prescribing Note |
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