Monograph Details
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Gastrointestinal Tract
> Hyperacidity, GERD, and ulcers
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PREVACID I.V. |
| Manufacturer |
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TAP Pharmaceutical Products, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Acid pump inhibitor. |
| Generic Name |
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Lansoprazole 30mg/vial; pwd for IV infusion after reconstitution and dilution. |
| Also |
• PREVACID
• PREVACID for ORAL SUSP
• PREVACID SOLUTAB
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| Indications |
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Short-term alternative to oral therapy for erosive esophagitis. |
| Children |
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Not recommended. |
| Adults |
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Infuse IV over 30 minutes (use filter). 30mg once daily for up to 7 days; switch to oral form as soon as possible (max 8 weeks therapy). |
| Precautions |
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Severe hepatic impairment (consider dose reduction). Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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May alter absorption of pH-dependent drugs (eg, ketoconazole, digoxin, iron, ampicillin). May antagonize atazanavir. Monitor theophylline, warfarin. Give at least 30 minutes before sucralfate. May give antacids concomitantly. |
| Adverse Reactions |
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Diarrhea, abdominal pain, nausea, constipation, headache, inj site reactions. |
| Extra Text |
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Note: See Amoxil or Trimox entry for more information on amoxicillin. See Biaxin entry for more information on clarithromycin. |
| How Supplied |
Caps 15mg—30, 1000
30mg—100, 1000
SoluTabs—30
Susp—30 packets/box
IV (single-dose vials)—10 |
| Additional Resources |
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• Related Prescribing Note |
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