Monograph Details

Gastrointestinal Tract > Hyperacidity, GERD, and ulcers
PEPCID INJECTION
Manufacturer
Merck & Co., Inc.
Legal Classification
Rx
Pharmacological Class
H2 blocker.
Generic Name
Famotidine 10mg/mL; soln for IV inj or infusion after dilution; multidose vials contain benzyl alcohol.
Also
PEPCID
PEPCID INJECTION PREMIXED
PEPCID SUSPENSION
Indications
Hospitalized patients with pathological hypersecretory conditions, intractable ulcers, or as a short-term alternative to oral dosage forms.
Children
See literature. Give by IV inj over 2 minutes or infuse over 15 minutes. <1yr: not recommended. 1–16yrs: initially 0.25mg/kg every 12hrs; max 40mg/day.
Adults
Give by IV inj over 2 minutes or infuse over 15–30 minutes. 20mg every 12 hrs.
Precautions
Moderate to severe renal insufficiency (CrCl <50mL/min): reduce dose or prolong dosing interval. Pregnancy (Cat.B). Nursing mothers: not recommended.
Interactions
May give antacids concomitantly.
Adverse Reactions
Headache, dizziness, constipation, diarrhea, somnolence, seizures, palpitations, depression, inj site reactions.
How Supplied
Tabs—30, 90, 100, 1000
Susp—50mL
Inj single-dose vials (2mL)—10
Multidose vials (4mL)—1
Multidose vials (20mL)—1, 10
Premixed (50mL)—1
Additional Resources
Related Prescribing Note