Monograph Details
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Gastrointestinal Tract
> Hyperacidity, GERD, and ulcers
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PEPCID INJECTION |
| Manufacturer |
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Merck & Co., Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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H2 blocker. |
| Generic Name |
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Famotidine 10mg/mL; soln for IV inj or infusion after dilution; multidose vials contain benzyl alcohol. |
| Also |
• PEPCID
• PEPCID INJECTION PREMIXED
• PEPCID SUSPENSION
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| Indications |
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Hospitalized patients with pathological hypersecretory conditions, intractable ulcers, or as a short-term alternative to oral dosage forms. |
| Children |
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See literature. Give by IV inj over 2 minutes or infuse over 15 minutes. <1yr: not recommended. 1–16yrs: initially 0.25mg/kg every 12hrs; max 40mg/day. |
| Adults |
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Give by IV inj over 2 minutes or infuse over 15–30 minutes. 20mg every 12 hrs. |
| Precautions |
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Moderate to severe renal insufficiency (CrCl <50mL/min): reduce dose or prolong dosing interval. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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May give antacids concomitantly. |
| Adverse Reactions |
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Headache, dizziness, constipation, diarrhea, somnolence, seizures, palpitations, depression, inj site reactions. |
| How Supplied |
Tabs—30, 90, 100, 1000 Susp—50mL Inj single-dose vials (2mL)—10 Multidose vials (4mL)—1 Multidose vials (20mL)—1, 10 Premixed (50mL)—1 |
| Additional Resources |
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• Related Prescribing Note |
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