Monograph Details
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Gastrointestinal Tract
> Hyperacidity, GERD, and ulcers
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IB-STAT |
| Manufacturer |
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Salix Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Anticholinergic. |
| Generic Name |
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Hyoscyamine sulfate 0.125 mg/spray; oral soln; apricot-peach flavor; contains alcohol, parabens. |
| Indications |
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Adjunct in irritable bowel syndrome, peptic ulcer. |
| Children |
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Not recommended. |
| Adults |
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1–2 sprays every 4 hours, or as needed, max 12 sprays/day. Do not rinse mouth for 5–10 minutes after use. |
| Contraindications |
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Glaucoma. Unstable cardiovascular status in acute hemorrhage. GI or urinary tract obstruction. Paralytic ileus, intestinal atony of elderly or debilitated patients. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis. |
| Precautions |
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Avoid eyes. High environmental temperature. Diarrhea. Autonomic neuropathy. Impaired cardiac or renal function. Cardiovascular disease. Hypertension. Hyperthyroidism. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Additive anticholinergic effects with other anticholinergics, amantadine, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics, MAOIs. |
| Adverse Reactions |
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Anticholinergic effects, drowsiness, excitement (esp. in elderly). |
| How Supplied |
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Spray—30mL (30 sprays) |
| Additional Resources |
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• Related Prescribing Note |
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