Monograph Details
|
|
Gastrointestinal Tract
> Hyperacidity, GERD, and ulcers
|
|
BENTYL SYRUP |
| Manufacturer |
|
Axcan Pharma |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Anticholinergic. |
| Generic Name |
|
Dicyclomine HCl 10mg/5mL. |
| Also |
|
• BENTYL
|
| Indications |
|
Irritable bowel syndrome. |
| Children |
|
<6months: not recommended. ≥6months: consult manufacturer. |
| Adults |
|
Initially 20mg 4 times daily; increase to 40mg 4 times daily if tolerated. Discontinue if not effective within 2 weeks or daily doses ≥80mg are not tolerated. |
| Contraindications |
|
Glaucoma. Unstable cardiovascular status. GI or urinary tract obstruction. Paralytic ileus or intestinal atony. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis. Reflux esophagitis. Children <6months of age. Nursing mothers. |
| Precautions |
|
Autonomic neuropathy. Impaired hepatic, cardiac, or renal function. Cardiovascular disease. Hypertension. Hyperthyroidism. GI or GU obstruction. High environmental temperature. Diarrhea. Elderly. Debilitated. Pregnancy (Cat.B). |
| Interactions |
|
Antacids may inhibit absorption. Potentiated CNS depression with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics, narcotic analgesics, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics. May affect absorption of sust rel dosage forms. |
| Adverse Reactions |
|
Drowsiness, anticholinergic effects. Fatal reactions have occurred in infants. |
| How Supplied |
Caps, tabs—100
Syrup—pt |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
