Monograph Details
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Gastrointestinal Tract
> Hyperacidity, GERD, and ulcers
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AMOXIL |
| Manufacturer |
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GlaxoSmithKline Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Broad-spectrum penicillin antibiotic. |
| Generic Name |
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Amoxicillin (as trihydrate) 500mg; caps. |
| Indications |
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In combination with lansoprazole and/or clarithromycin to eradicate H. pylori in adults with duodenal ulcer disease. |
| Children |
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Not recommended. |
| Adults |
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Triple therapy: amoxicillin 1g + clarithromycin 500mg + lansoprazole 30mg, all every 12 hrs for 14 days. Dual therapy (if allergic or resistant to clarithromycin): amoxicillin 1g + lansoprazole 30mg, both every 8 hrs for 14 days. |
| Precautions |
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Cephalosporin, imipenem, other allergy or mononucleosis: not recommended. Monitor blood, renal, and hepatic function in long-term use. Labor & delivery. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Potentiated by probenecid. May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. |
| Adverse Reactions |
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Diarrhea, headache, hypersensitivity reactions (eg, urticaria, rash, Stevens-Johnson syndrome, anaphylaxis), blood dyscrasias. Triple therapy: taste perversion. |
| Extra Text |
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Note: See Biaxin entry for more information on clarithromycin. See Prevacid entry for more information on lansoprazole. |
| How Supplied |
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Caps—500 |
| Additional Resources |
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• Related Prescribing Note |
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