Monograph Details
|
|
Gastrointestinal Tract
> Digestive and biliary disorders
|
|
URSO |
| Manufacturer |
|
Axcan Pharma |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Bile acid. |
| Generic Name |
|
Ursodiol 250mg; tabs. |
| Also |
|
• URSO FORTE
|
| Indications |
|
Primary biliary cirrhosis. |
| Children |
|
Not recommended. |
| Adults |
|
Take with food. 13–15mg/kg per day in 2–4 divided doses. |
| Precautions |
|
Variceal bleeding, hepatic encephalopathy, ascites, and/or need for an urgent liver transplant: give appropriate specific treatment. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
|
Reduced absorption with bile acid sequestrants (e.g., cholestyramine, colestipol), and aluminum-containing antacids. Estrogens, oral contraceptives, clofibrate, other lipid-lowering drugs may reduce effectiveness of ursodiol by increasing hepatic cholesterol secretion. |
| Adverse Reactions |
|
Leukopenia, rash, GI effects, elevated creatinine or blood glucose. |
| How Supplied |
|
Tabs—100, 500 |
|
|
|
|
