Monograph Details
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Gastrointestinal Tract
> Diarrhea
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VANCOCIN |
| Manufacturer |
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ViroPharma |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antibiotic. |
| Generic Name |
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Vancomycin (as HCl) 125mg, 250mg; caps. |
| Indications |
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Enterocolitis due to S. aureus. Antibiotic-associated pseudomembranous colitis due to C. difficile. |
| Children |
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40mg/kg per day in 3–4 divided doses for 7–10 days; max 2g/day. |
| Adults |
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500mg–2g per day in 3–4 divided doses for 7–10 days. |
| Precautions |
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Renal insufficiency. Underlying hearing loss. Inflammatory bowel disorders. Monitor blood, renal, and auditory function. Consider monitoring vancomycin serum concentrations. Children. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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Other neurotoxic, nephrotoxic, or ototoxic drugs (eg, aminoglycosides) may increase risk of toxicity; monitor. |
| Adverse Reactions |
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Nausea, drug fever, urticaria, rash (may be serious, eg, Stevens-Johnson syndrome), ototoxicity, nephrotoxicity, eosinophilia, anaphylaxis and anaphylactoid reactions (eg, "Red Man Syndrome"), superinfection, blood dyscrasias; rare: interstitial nephritis, vertigo, vasculitis. |
| How Supplied |
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Caps—20 |
| Additional Resources |
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• Related Prescribing Note |
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