Monograph Details
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Gastrointestinal Tract
> Colorectal disorders
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CORTENEMA |
| Manufacturer |
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Solvay Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Steroid. |
| Generic Name |
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Hydrocortisone 100mg/60mL; enema. |
| Indications |
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Adjunct in ulcerative colitis. |
| Children |
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Not recommended. |
| Adults |
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1 enema nightly for 21 days or until symptoms controlled; discontinue if no improvement within 2–3 weeks. |
| Contraindications |
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Systemic fungal infections. Vaccinations. Postileocolostomy. |
| Precautions |
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Tuberculosis. Stress. Exacerbation or masking of infections. Diverticulitis. Impending perforation or abscess. Fresh intestinal anastomoses or obstruction. Fistulas. Sinus tracts. Peptic ulcer. Renal dysfunction. Hepatic cirrhosis. Hypertension. Osteoporosis. Myasthenia gravis. Hypo- or hyperthyroidism. Ocular herpes simplex. Psychosis. Monitor adrenal function and serum electrolytes. Avoid abrupt cessation after prolonged use. Pregnancy. Nursing mothers. |
| Interactions |
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May antagonize insulin or oral hypoglycemics, anticoagulants, aspirin. Hypokalemia with amphotericin B or diuretics. |
| Adverse Reactions |
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Hypertension, fluid retention, hypokalemia, adrenal suppression, poor wound healing, cataracts, glaucoma, psychosis, dysmenorrhea, myopathy, neuropathy, thrombophlebitis, peptic ulcer, convulsions, local irritation: folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, macerations, dermal and epidermal atrophy, secondary infections, striae, miliaria, local pain or burning. |
| How Supplied |
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Enemas—1, 7 |
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