Monograph Details

Eye Disorders > Ocular infections
CILOXAN
Manufacturer
Alcon Laboratories, Inc.
Legal Classification
Rx
Pharmacological Class
Quinolone.
Generic Name
Ciprofloxacin (as HCl) 0.3%; oph. soln; contains benzalkonium chloride.
Also
CILOXAN OPH OINT
Indications
Susceptible infections of conjunctiva and cornea.
Adults and Children
<1 year: not recommended. ≥1 year: Conjunctivitis: 1–2 drops in conjunctival sac(s) every 2 hours while awake for 2 days, then 1–2 drops every 4 hours while awake for next 5 days. Corneal ulcers: 2 drops every 15 minutes for 1st 6 hours, then 2 drops every 30 minutes for rest of 1st day; 2nd day: 2 drops every 1 hour; 3rd–14th days: 2 drops every 4 hours. May treat for 14 days or until corneal reepithelialization occurs.
Precautions
CNS or convulsive disorders. Discontinue if rash occurs. Pregnancy (Cat.C). Nursing mothers.
Interactions
May increase theophylline levels. May potentiate oral anticoagulants. May increase renal toxicity with cyclosporine.
Adverse Reactions
Soln: Burning, crystalline precipitates, lid margin crusting, scales, foreign body sensation, pruritus, conjunctival hyperemia, bad taste. Oint: ocular discomfort, blurred vision; may delay corneal healing. Both: superinfection.
How Supplied
Soln—2.5 mL, 5 mL, 10 mL
Oint—3.5 g
Additional Resources
Related Prescribing Note