Monograph Details

Eye Disorders > Ocular allergy/inflammation
NEVANAC
Manufacturer
Alcon Laboratories, Inc.
Legal Classification
Rx
Pharmacological Class
NSAID.
Generic Name
Nepafenac 0.1%, oph. susp; contains benzalkonium chloride.
Indications
Post-operative pain and inflammation following cataract surgery.
Children
<10yrs: not recommended.
Adults
≥10yrs: 1 drop in affected eye(s) 3 times daily starting one day before surgery, continued on day of surgery, and through first 2 weeks post-op.
Precautions
Bleeding tendencies. May delay wound healing. Complicated/repeat ocular surgeries. Corneal defects/denervation. Ocular surface diseases. Rheumatoid arthritis. Diabetes. Monitor cornea; discontinue if corneal epithelial breakdown occurs. Contact lenses (remove during therapy). Risk of corneal adverse events may be increased if used more than 24 hours before surgery, or beyond 14 days post-op. Pregnancy (Cat.C; avoid during 3rd trimester). Nursing mothers.
Interactions
May potentiate oral anticoagulants, others that prolong bleeding.
Adverse Reactions
Ocular effects (eg, capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, sticky sensation, edema, dry eye, lid margin crusting, discomfort, hyperemia, pain, pruritus, photophobia, tearing, vitreous detachment), headache, hypertension, GI upset, sinusitis.
How Supplied
Susp—3mL