Monograph Details
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Eye Disorders
> Ocular allergy/inflammation
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BLEPHAMIDE |
| Manufacturer |
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Allergan |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Sulfonamide + steroid. |
| Generic Name |
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Sulfacetamide sodium 10%, prednisolone acetate 0.2%; oph susp; contains benzalkonium chloride. |
| Also |
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• BLEPHAMIDE S.O.P. OINT
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| Indications |
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Ocular inflammation with infection. |
| Adults and Children |
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<6 years: not recommended. ≥6 years: 2 drops every 4 hours and at bedtime or small amount of ointment 3–4 times daily and 1–2 times at night. May prolong dosing interval as condition improves; max 20 mL or 8 g per therapeutic course. |
| Contraindications |
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Ocular fungal, viral, or mycobacterial infections. |
| Precautions |
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Corneal or scleral thinning. Glaucoma. Myopia. Diabetes. Purulent exudates may inactivate sulfonamides. Monitor for secondary infections and intraocular pressure in prolonged use. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Incompatible with silver-containing preparations. Antagonized by PABA. |
| Adverse Reactions |
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Ocular irritation, secondary infections; rarely: severe sulfonamide sensitivity reactions (Stevens-Johnson syndrome, fever, bone marrow depression, lupus). In prolonged use: increased IOP, cataracts, corneal perforations, optic nerve damage. May mask signs of infection or retard corneal healing. |
| How Supplied |
Susp—5mL, 10mL
Oint—3.5g |
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