Monograph Details
|
|
Eye Disorders
> Glaucoma
|
|
TRUSOPT |
| Manufacturer |
|
Merck & Co., Inc. |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Carbonic anhydrase inhibitor (sulfonamide). |
| Generic Name |
|
Dorzolamide HCl 2%; oph soln; contains benzalkonium chloride. |
| Indications |
|
Open-angle glaucoma. Ocular hypertension. |
| Adults and Children |
|
1 drop 3 times daily. |
| Precautions |
|
Hepatic impairment. Severe renal impairment (CrCl <30mL/min): not recommended. Discontinue if ocular effects (eg, conjunctivitis, lid reactions) occur. Soft contact lenses. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
|
Concomitant oral carbonic anhydrase inhibitors: not recommended. May inhibit renal excretion of basic drugs and promote excretion of acidic drugs. May increase salicylate toxicity (acidosis). |
| Adverse Reactions |
|
Burning, stinging, bitter taste, punctate keratitis, ocular allergic reaction, blurred vision, tearing, dryness, photophobia; possible sulfa-like systemic effects. |
| How Supplied |
|
Soln—10mL |
|
|
|
|
