Monograph Details
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Eye Disorders
> Glaucoma
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DIAMOX SEQUELS |
| Manufacturer |
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Duramed Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Carbonic anhydrase inhibitor. |
| Generic Name |
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Acetazolamide 500mg; sust rel caps. |
| Indications |
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Adjunct in open-angle glaucoma. |
| Children |
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Not recommended. |
| Adults |
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500mg twice daily. |
| Contraindications |
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Hypokalemia. Hyponatremia. Severe renal, hepatic, or adrenocortical impairment. Hyperchloremic acidosis. Cirrhosis. Chronic noncongestive angle-closure glaucoma. Sulfonamide allergy. |
| Precautions |
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Respiratory impairment. Renal calcium calculi. Diabetes. Gout. Test blood periodically in chronic use. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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May inhibit renal excretion of basic drugs and promote excretion of acidic drugs. May increase salicylate toxicity (acidosis). Hypokalemia with corticosteroids, potassium wasting diuretics. |
| Adverse Reactions |
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Anorexia, drowsiness, confusion, malaise, depression, GI distress, paresthesias, tinnitus, acidosis, initial hypokalemia, hyperuricemia, transient myopia; renal calculi, nephrotoxicity, hepatic dysfunction, blood dyscrasias, rash, fever, photosensitivity (rare). |
| How Supplied |
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Caps—100 |
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