Monograph Details
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Eye Disorders
> Glaucoma
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AZOPT |
| Manufacturer |
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Alcon Laboratories, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Carbonic anhydrase inhibitor (sulfonamide). |
| Generic Name |
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Brinzolamide 1%; oph. susp; contains benzalkonium chloride. |
| Indications |
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Open-angle glaucoma. Ocular hypertension. |
| Children |
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Not recommended. |
| Adults |
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1 drop 3 times daily. |
| Precautions |
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Hepatic impairment. Severe renal impairment (CrCl <30mL/min): not recommended. Discontinue if serious systemic, ocular (eg, conjunctivitis, lid edema), or hypersensitivity reactions occur. Soft contact lenses (remove; may reinsert 15 minutes after administration). Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Concomitant oral carbonic anhydrase inhibitors: not recommended. Separate administration of other oph drugs by ≥10 minutes. |
| Adverse Reactions |
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Blurred vision, bitter/sour taste, blepharitis, dermatitis, dry eye, foreign body sensation, headache, hyperemia; ocular discharge, discomfort, or itch; keratitis, rhinitis. |
| How Supplied |
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Susp—2.5mL, 5mL, 10mL, 15mL |
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