Monograph Details
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Eye Disorders
> Glaucoma
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ALPHAGAN P |
| Manufacturer |
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Allergan |
| Legal Classification |
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Rx
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| Pharmacological Class |
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α2-agonist. |
| Generic Name |
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Brimonidine tartrate 0.1%, 0.15%; oph. soln; contains purite. |
| Indications |
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Open-angle glaucoma. Ocular hypertension. |
| Adults and Children |
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<2yrs: not recommended. ≥2yrs: 1 drop every 8 hours. |
| Contraindications |
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Concomitant MAOIs. |
| Precautions |
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Severe cardiovascular disease. Hepatic or renal impairment. Depression. Cerebral or coronary insufficiency. Raynaud's phenomenon. Orthostatic hypotension. Thromboangiitis obliterans. Remove soft contact lenses before use; may reinsert 15 minutes later. Monitor for loss of effect. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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MAOIs: see Contraindications. Caution with CNS depressants, antihypertensives, cardiac glycosides, tricyclic antidepressants. Separate administration of other oph drugs by ≥5 minutes. |
| Adverse Reactions |
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Oral dryness, ocular hyperemia, burning, stinging, headache, blurred or abnormal vision, foreign body sensation, fatigue, drowsiness, conjunctival follicles, ocular allergic reactions or pruritus, corneal staining/erosion, photophobia, ocular discomfort or dryness, tearing, upper respiratory symptoms, conjunctival blanching, muscular pain, others. |
| How Supplied |
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Soln—5mL, 10mL, 15mL |
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