Monograph Details
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Endocrine System
> Thyroid disease
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THYROLAR 1/2 |
| Manufacturer |
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Forest Laboratories |
| Legal Classification |
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Rx
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| Pharmacological Class |
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T3 and T4 (synthetic). |
| Generic Name |
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Liotrix (contains liothyronine sodium (T3) 6.25micrograms and levothyroxine sodium (T4) 25micrograms); tabs. |
| Also |
• THYROLAR 1
• THYROLAR 1/4
• THYROLAR 2
• THYROLAR 3
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| Indications |
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Hypothyroidism. |
| Children |
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Hypothyroidism: <6months: one tab of Thyrolar 1/4 to one tab of Thyrolar 1/2 daily. 6–12months: one tab of Thyrolar 1/2 to one tab of Thyrolar 1/2 + one tab of Thyrolar 1/4 daily; 1–5yrs: one tab of Thyrolar 1/2 + one tab of Thyrolar 1/4 to one tab of Thyrolar 1 daily; 6–12yrs: one tab of Thyrolar 1 to one tab of Thyrolar 1 + one tab of Thyrolar 1/2 daily; >12yrs: more than one tab of Thyrolar 1 + one tab of Thyrolar 1/2 daily. |
| Adults |
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Hypothyroidism: initially one tab of Thyrolar 1/2 daily (long-standing myxedema: initially one tab of Thyrolar 1/4 daily); increase by one tab of Thyrolar 1/4 every 2–3 weeks; usual maintenance: one tab of Thyrolar 1 to one tab of Thyrolar 2 daily. Myxedema coma: see literature. |
| Contraindications |
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Uncorrected adrenocortical insufficiency. Untreated thyrotoxicosis. |
| Precautions |
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Not for treatment of obesity. Cardiovascular disease, angina, elderly: use lower initial dose. Adrenocortical insufficiency. Monitor for craniosynostosis in infants. Pregnancy (Cat. A). Nursing mothers. |
| Interactions |
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Monitor oral anticoagulants, hypoglycemics. Estrogens affect thyroid function tests. Toxicity with larger doses of sympathomimetics (e.g., anorectics). |
| Adverse Reactions |
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Hyperthyroidism; transient hair loss in children. |
| How Supplied |
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Tabs—100 |
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