Monograph Details
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Endocrine System
> Diabetes
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NOVOLOG MIX 70/30 |
| Manufacturer |
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Novo Nordisk |
| Legal Classification |
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Rx
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| Generic Name |
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Insulin aspart protamine suspension 70% (recombinant), insulin aspart 30% (recombinant) 100 Units/mL; SC inj; contains zinc, m-cresol. |
| Indications |
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Diabetes. |
| Children |
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Not recommended. |
| Adults |
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For SC inj only. Onset approx ≤15 minutes, peak approx 1–4 hours, duration up to 24 hours. |
| Precautions |
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Instruct patients on diet, exercise, blood or urine testing, proper administration of insulin, change in species of origin, type or purity of insulin, and management of hypoglycemia. Dosage increase may be required during infection, illness, stress, trauma, and pregnancy. Dosage decrease may be needed with renal or hepatic dysfunction. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Potentiated by salicylates, MAOIs, alcohol, sulfa drugs, some ACE inhibitors, drugs that inhibit pancreatic function (eg, octreotide). Antagonized by corticosteroids, isoniazid, niacin, thiazides, phenothiazines, sympathomimetics. Variable effects with β-blockers, clonidine, lithium salts, alcohol. |
| Adverse Reactions |
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Hypoglycemia, hypokalemia, local or systemic allergy, lipodystrophy, edema. |
| How Supplied |
Vials (10mL)—1
FlexPen (3mL prefilled syringe)—1
PenFill (3mL cartridges)—1
NovoPen 3 (inj device, uses PenFill cartridges)—1
NovoLog NovoPen Junior (inj device, uses PenFill cartridges)—1 |
| Additional Resources |
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• Related Prescribing Note |
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