Monograph Details
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Endocrine System
> Corticosteroid-responsive disorders
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ARISTOCORT |
| Manufacturer |
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Astellas Pharma US, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Glucocorticoid. |
| Generic Name |
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Triamcinolone 4mg; scored tabs. |
| Also |
• ARISTOCORT FORTE
• ARISTOCORT INTRALESIONAL
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| Indications |
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Steroid-responsive disorders. |
| Adults and Children |
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See literature. Usual initial dose 4–48mg/day. |
| Contraindications |
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Systemic mycoses. Live vaccination. |
| Precautions |
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Avoid injection into previously infected or unstable joints. Tuberculosis. Latent amebiasis. Varicella. Vaccinia. Hypothyroidism. Cirrhosis. Ocular herpes simplex. If exposed to chickenpox or measles, consider prophylactic passive immune therapy. Renal insufficiency. Ulcerative colitis if perforation pending. Diverticulitis. Peptic ulcer. Hypertension. Osteoporosis. Diabetes. Supplement with additional steroids in physiologic stress. Avoid abrupt cessation. Alternate, intermittent or single-daily doses at 8AM minimize adrenal suppression. Monitor weight, growth, fluid and electrolyte balance. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Barbiturates, hydantoins, rifampin may decrease effects. Avoid aspirin in hypoprothrombinemia. |
| Adverse Reactions |
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HPA axis suppression, masks infection, increased susceptibility to infection, glaucoma, cataracts, secondary infections, hypokalemia, hypocalcemia, hypernatremia, hypertension, psychic disorders, myopathy, osteoporosis, peptic ulcer, dermal atrophy, increased intracranial pressure, carbohydrate intolerance. Parenteral: atrophy or flare (intraarticular use) at inj site. |
| How Supplied |
Tabs—30, 100
Forte (1mL, 5mL)—1
Intalesional (5mL)—1 |
| Additional Resources |
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• Related Prescribing Note |
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