Monograph Details
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Dermatological Disorders
> Scabies and lice
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Lindane Lotion |
| Manufacturer |
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Various generic manufacturers |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Pediculicide. |
| Generic Name |
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Lindane 1%. |
| Also |
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• Lindane Shampoo
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| Indications |
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Treatment of scabies in patients who have failed on, or are intolerant of, other therapies. Not for prophylactic use. |
| Adults and Children |
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Treat once only. Use least amount to cover body. <110lbs: not recommended. ≥110lbs: average size adult: 30mL; larger adult: max 60mL. Apply sparingly to dry skin; leave on for 8–12 hours then wash off thoroughly. |
| Contraindications |
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Uncontrolled seizure disorders. Premature infants. Norwegian (crusted) scabies, other skin conditions (eg, eczema, psoriasis, broken skin) that may increase absorption. |
| Precautions |
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Potential CNS toxicity if absorbed. Children, infants, elderly, patients <110lbs: increased neurotoxicity risk. Seizure risk (eg, history of head trauma, prior seizures, CNS tumor, HIV infection, hepatic cirrhosis, abrupt alcohol/sedative withdrawal). Itching may occur or worsen after successful treatment; do not retreat. Avoid eyes. Do not swallow or misuse. Pregnancy (Cat.C), nursing mothers: not recommended. |
| Interactions |
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Systemic absorption and toxicity may be increased by oils, creams, ointments. Caution with drugs that lower seizure threshold (eg, antipsychotics, antidepressants, quinolones, theophylline, cyclosporine). |
| Adverse Reactions |
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Irritation, post-treatment pruritus, CNS stimulation (eg, dizziness, convulsions). |
| How Supplied |
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Both—1oz, 2oz |
| Additional Resources |
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• Related Prescribing Note |
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