Monograph Details
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Dermatological Disorders
> Miscellaneous dermatological conditions
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CARAC |
| Manufacturer |
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Dermik Laboratories |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antimetabolite. |
| Generic Name |
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Fluorouracil 0.5% (0.35% in microspheres); crm. |
| Indications |
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Multiple actinic or solar keratoses of the face and anterior scalp. |
| Children |
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<18yrs: not recommended. |
| Adults |
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≥18yrs: Wash and dry area. Wait 10 minutes. Apply thin film to skin where lesions appear once daily for up to 4 weeks. Do not occlude. May apply sunscreen/ moisturizer 2 hours later. Wash hands after use. |
| Contraindications |
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Dihydropyrimidine dehydrogenase (DPD) deficiency. Women of childbearing potential. Pregnancy (Cat.X). |
| Precautions |
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Discontinue if symptoms of DPD deficiency develop (e.g., abdominal pain, bloody diarrhea, vomiting, fever, chills). Ulcerated or inflamed skin. Avoid eyes, mucous membranes, exposure to sun or UV light. Nursing mothers: not recommended. |
| Adverse Reactions |
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Application site reaction (may persist 2 weeks after drug is stopped), eye irritation. |
| How Supplied |
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Crm—30g |
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