Monograph Details
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Dermatological Disorders
> Acne
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ZIANA |
| Manufacturer |
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Medicis Pharmaceuticals Corp |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Lincosamide + retinoid. |
| Generic Name |
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Clindamycin phosphate 1.2%; tretinoin 0.025%; gel. |
| Indications |
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Acne vulgaris. |
| Children |
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Not recommended. |
| Adults |
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Apply thin film to clean, dry face once daily at bedtime. |
| Contraindications |
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Regional enteritis. Ulcerative colitis. History of antibiotic-associated colitis. |
| Precautions |
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Sunburn (allow to heal before using). Avoid sun, UV light, eyes, mouth, angles of nose, mucous membranes. Discontinue if significant diarrhea occurs. Increased irritation in extreme weather. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Avoid erythromycin. Additive irritation with other topical products (eg, alcohol, drying agents, lime). May potentiate neuromuscular blockers. Caution with other photosensitizers (eg, tetracyclines, quinolones). |
| Adverse Reactions |
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Erythema, scaling, itching, burning, stinging, nasopharyngitis, throat pain, dry skin, cough, sinusitis; rare: diarrhea, colitis. |
| How Supplied |
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Gel—2g, 30g, 60g |
| Additional Resources |
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• Related Prescribing Note |
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