Monograph Details
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Dermatological Disorders
> Acne
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MINOCIN |
| Manufacturer |
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Triax Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Tetracycline antibiotic. |
| Generic Name |
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Minocycline (as HCl) 50mg, 100mg; pellet-filled caps. |
| Indications |
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Adjunct in severe acne. |
| Children |
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Swallow whole. Take on empty stomach with fluids.<8 years: not recommended. >8 years: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours. |
| Adults |
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Swallow whole. Take on empty stomach with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily. |
| Precautions |
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Renal or hepatic impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy (Cat.D), nursing mothers: not recommended. |
| Interactions |
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Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid penicillins, methoxyflurane, isotretinoin. Monitor PT with oral anticoagulants. May antagonize oral contraceptives. |
| Adverse Reactions |
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Dizziness, GI upset, rash, pseudotumor cerebri, blood dyscrasias, increased BUN, interstitial nephritis, hepatotoxicity, tinnitus, tooth discoloration; rare: photosensitivity. |
| How Supplied |
Caps—60
Minocin PAC—60 caps (50mg or 100mg) + serum, wipes, masque |
| Additional Resources |
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• Related Prescribing Note |
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