Monograph Details
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Dermatological Disorders
> Acne
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DORYX |
| Manufacturer |
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Warner Chilcott Laboratories |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Tetracycline antibiotic. |
| Generic Name |
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Doxycycline (as hyclate) 75mg, 100mg; del-rel tabs. |
| Indications |
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Adjunct in severe acne. |
| Children |
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Not applicable. |
| Adults |
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Take with fluids. 100mg every 12 hrs for 1 day, then 100mg daily; reduce dose after improvement. |
| Precautions |
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Monitor blood, renal, and hepatic function in long-term use. Sunlight or UV light. Labor & delivery. Pregnancy (Cat.D), nursing mothers: usually not recommended. |
| Interactions |
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Antacids, iron, zinc, calcium, magnesium, bismuth subsalicylate reduce absorption. Avoid concomitant penicillins, methoxyflurane. Carbamazepine, barbiturates, hydantoins decrease effectiveness. Monitor prothrombin time with oral anticoagulants. Oral contraceptives may be less effective. |
| Adverse Reactions |
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Photosensitivity, GI upset, rash, blood dyscrasias, hepatotoxicity. |
| How Supplied |
Tabs 75mg—60
100mg—100 |
| Additional Resources |
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• Related Prescribing Note |
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