Monograph Details
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Central Nervous System
> Psychosis
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Haloperidol Tablets |
| Manufacturer |
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Various generic manufacturers |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Butyrophenone. |
| Generic Name |
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Haloperidol 0.5mg, 1mg, 2mg, 5mg, 10mg, 20mg; scored tabs. |
| Indications |
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Psychosis. Tourette's disorder. For severe behavior disorders or as a short-term treatment for hyperactivity in children who are refractory to psychotherapy or other medications. |
| Children |
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<3yrs: not recommended. Total dose may be divided, to be given 2–3 times daily. ≥3yrs: initially 0.5mg daily, may increase at increments of 0.5mg at 5–7 day intervals. Psychosis: 0.05mg/kg/day–0.15mg/kg/day. Nonpsychotic behavior and Tourette's: 0.05mg/kg/day–0.075mg/kg/day. Max 6mg/day. |
| Adults |
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Individualize. Initially: Moderate symptoms: 0.5mg–2mg 2–3 times daily. Severe, chronic, or resistant symptoms: 3mg–5mg 2–3 times daily. Debilitated: 0.5mg–2mg 2–3 times daily. Max: 100mg/day. |
| Elderly |
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Initially 0.5mg–2mg 2–3 times daily. |
| Contraindications |
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Severe CNS depression. Coma. Parkinsonism. |
| Precautions |
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Cardiovascular disease. History of seizures. Thyrotoxicosis. Avoid abrupt cessation. Elderly. Debilitated. Pregnancy. Nursing mothers: not recommended. |
| Interactions |
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CNS depression potentiated with alcohol, other CNS depressants. Possible neurotoxicity with lithium; monitor closely, discontinue if occurs. May increase intraocular pressure with anticholinergics. Monitor anticoagulants. |
| Adverse Reactions |
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Tardive dyskinesia, extrapyramidal symptoms, CNS effects, GI upset, cardiovascular effects, bronchopneumonia, neuroleptic malignant syndrome. |
| How Supplied |
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Contact supplier. |
| Additional Resources |
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• Related Prescribing Note |
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