Monograph Details
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Central Nervous System
> Psychosis
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HALDOL INJECTION |
| Manufacturer |
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Ortho-McNeil Neurologics, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Butyrophenone. |
| Generic Name |
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Haloperidol (as lactate) 5mg/mL. |
| Also |
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• HALDOL DECANOATE INJ
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| Indications |
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Schizophrenia. Tourette's disorder. |
| Children |
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Not recommended. |
| Adults |
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2–5mg IM every 4–8 hrs or up to hourly if needed. Switch to oral form 12–24 hrs after last injection. |
| Contraindications |
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Severe CNS depression. Coma. Parkinsonism. |
| Precautions |
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Cardiovascular disease. QT-prolonging conditions. Electrolyte disturbances (eg, hypokalemia, hypomagnesemia). Hypothyroidism. Seizures. Thyrotoxicosis. Avoid abrupt cessation. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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CNS depression potentiated with alcohol, other CNS depressants. Possible neurotoxicity with lithium: monitor, discontinue if occurs. Caution with drugs that prolong the QT interval. Monitor anticoagulants, rifampin. |
| Adverse Reactions |
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Tardive dyskinesia, neuroleptic malignant syndrome, extrapyramidal symptoms, hyperpyrexia, heat stroke, bronchopneumonia, cardiovascular effects, GI upset, anticholinergic effects; QT prolongation, Torsades de Pointes. |
| How Supplied |
Inj (1mL amps)—10
Decanoate 50 (1mL amps)—3, 10
Decanoate 100 (1mL amps)—5 |
| Additional Resources |
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• Related Prescribing Note |
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