Monograph Details
|
|
Central Nervous System
> Parkinsonism
|
|
COGENTIN INJECTION |
| Manufacturer |
|
Ovation Pharmaceuticals, Inc. |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Anticholinergic. |
| Generic Name |
|
Benztropine mesylate 1mg/mL; soln for IM or IV inj. |
| Also |
|
• Benztropine
|
| Indications |
|
Adjunct in Parkinsonism, drug-induced extrapyramidal disorders. |
| Children |
|
<3 yrs: not recommended. Use cautiously in older children. |
| Adults |
|
Parkinsonism: initially 0.5–1mg at bedtime. May increase by 0.5mg at 5–6 day intervals; max 6mg daily. Extrapyramidal disorders: 1–4mg 1–2 times daily. Acute dystonic reactions: 1–2mg IM or IV. |
| Contraindications |
|
Tardive dyskinesia. Narrow-angle glaucoma. |
| Precautions |
|
Tachycardia. Psychosis. Prostatic hypertrophy. GI or GU obstruction. Chronically ill. Alcoholics. CNS disease. Exposure to extreme heat. Monitor intraocular pressure. Pregnancy. |
| Interactions |
|
Paralytic ileus, hyperthermia, heat stroke with phenothiazines, tricyclic antidepressants. Antagonizes psychotropics. |
| Adverse Reactions |
|
Drowsiness, anticholinergic and antihistaminic effects, weakness, confusion, anhidrosis, excitement, GI upset, depression, lethargy, heat stroke, dysuria, toxic psychosis, rash. |
| How Supplied |
Tabs—contact supplier.
Amps—(5 x 2mL) |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
