Monograph Details
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Central Nervous System
> Parkinsonism
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Benztropine |
| Manufacturer |
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Various generic manufacturers |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Anticholinergic. |
| Generic Name |
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Benztropine mesylate 0.5mg, 1mg, 2mg; scored tabs. |
| Also |
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• COGENTIN INJECTION
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| Indications |
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Adjunct in Parkinsonism, drug-induced extrapyramidal disorders. |
| Children |
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<3 yrs: not recommended. Use cautiously in older children. |
| Adults |
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Parkinsonism: initially 0.5–1mg at bedtime. May increase by 0.5mg at 5–6 day intervals; max 6mg daily. Extrapyramidal disorders: 1–4mg 1–2 times daily. Acute dystonic reactions: 1–2mg IM or IV. |
| Contraindications |
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Tardive dyskinesia. Narrow-angle glaucoma. |
| Precautions |
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Tachycardia. Psychosis. Prostatic hypertrophy. GI or GU obstruction. Chronically ill. Alcoholics. CNS disease. Exposure to extreme heat. Monitor intraocular pressure. Pregnancy. |
| Interactions |
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Paralytic ileus, hyperthermia, heat stroke with phenothiazines, tricyclic antidepressants. Antagonizes psychotropics. |
| Adverse Reactions |
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Drowsiness, anticholinergic and antihistaminic effects, weakness, confusion, anhidrosis, excitement, GI upset, depression, lethargy, heat stroke, dysuria, toxic psychosis, rash. |
| How Supplied |
Tabs—contact supplier.
Amps—(5 x 2mL) |
| Additional Resources |
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• Related Prescribing Note |
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