Monograph Details
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Central Nervous System
> Mood disorders
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REMERON SOLTAB |
| Manufacturer |
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Schering Corporation |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Tetracyclic. |
| Generic Name |
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Mirtazapine 15mg, 30mg, 45mg; orally-disintegrating tabs; orange flavor; contains phenylalanine. |
| Also |
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• REMERON
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| Indications |
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Depression. |
| Children |
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Not recommended. |
| Adults |
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Initially 15mg once daily at bedtime; increase at intervals of at least 1–2 weeks. Usual range: 15–45mg daily. SolTab: Dissolve on tongue and swallow with or without water. |
| Contraindications |
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During or within 14 days of MAOIs. |
| Precautions |
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Hepatic or moderate to severe renal dysfunction. Diseases that affect metabolism or hemodynamic response. History of mania/hypomania. Seizure disorders. Suicidal ideation. History of MI. Angina. Ischemic stroke. Hypovolemia. Elderly. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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See Contraindications. Possible serious/fatal reactions with MAOIs. Potentiation with alcohol, diazepam, other CNS depressants. Caution with drugs metabolized by and/or that inhibit CYP450. |
| Adverse Reactions |
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Somnolence, increased appetite, weight gain, dizziness, nausea, dry mouth, constipation, asthenia, flu syndrome, edema, CNS effects; hypo- or hypertension, elevated cholesterol, triglycerides, or transaminases; agranulocytosis (rare). |
| How Supplied |
Tabs 15mg, 30mg—30, 100
45mg—30
SolTabs—30 |
| Additional Resources |
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• Related Prescribing Note |
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