Monograph Details
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Central Nervous System
> Anxiety/OCD
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Lorazepam INTENSOL |
| Manufacturer |
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Roxane Laboratories, Inc. |
| Legal Classification |
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CIV |
| Pharmacological Class |
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Benzodiazepine. |
| Generic Name |
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Lorazepam 2mg; per mL; concentrated soln. |
| Indications |
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Anxiety. |
| Children |
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Not recommended. |
| Adults |
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Mix with liquid or semi-solid food. Consume mixture immediately. Give in 2 or 3 divided doses, with largest dose taken at bedtime. Anxiety: initially 2–3mg daily; range: 1–10mg daily. Elderly or debilitated: initially 1–2mg daily; adjust gradually if needed. Transient stress or insomnia: 2–4mg single daily dose at bedtime. |
| Contraindications |
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Acute narrow-angle glaucoma. |
| Precautions |
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Drug or alcohol abuse. Suicidal tendencies. Renal or hepatic dysfunction. Therapy for >4months. Monitor blood counts and liver function with long-term use. Avoid abrupt cessation. Elderly. Debilitated. Psychosis, depression, pregnancy, nursing mothers: not recommended. |
| Interactions |
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Potentiation of CNS depression with alcohol, other CNS depressants. |
| Adverse Reactions |
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CNS depression (esp. sedation), dizziness, weakness, unsteadiness, transient memory impairment, disorientation, nausea, headache, sleep disturbances, agitation, abuse potential, upper GI disease (monitor). |
| How Supplied |
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Soln—30mL (w. dropper) |
| Additional Resources |
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• Related Prescribing Note |
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