Monograph Details
|
|
Central Nervous System
> Anxiety/OCD
|
|
LIBRIUM INJECTABLE |
| Manufacturer |
|
Valeant Pharmaceuticals, Inc |
| Legal Classification |
|
CIV |
| Pharmacological Class |
|
Benzodiazepine. |
| Generic Name |
|
Chlordiazepoxide HCl 100mg for IM or IV inj after reconstitution. |
| Also |
|
• LIBRIUM
|
| Indications |
|
Anxiety. |
| Children |
|
Not recommended. |
| Adults |
|
Initially 50–100mg IM or IV, then 25–50mg 3–4 times a day if needed; max 300mg/day. |
| Precautions |
|
Drug or alcohol abuse. Suicidal tendencies. Depression. Renal or hepatic disease. Therapy for >4 months. Porphyria. Psychosis. Epilepsy. Change dose gradually. Monitor blood counts and liver function. Elderly. Debilitated. Pregnancy, nursing mothers: not recommended. |
| Interactions |
|
Potentiates CNS depression with alcohol, other CNS depressants. Variable effects with anticoagulants. Avoid other psychotropics. |
| Adverse Reactions |
|
Drowsiness, CNS depression, ataxia, confusion, paradoxical excitement, memory impairment, blood dyscrasias, jaundice, rash, edema, extrapyramidal effects, abuse potential. |
| How Supplied |
Caps 5mg—100
10mg, 25mg—100, 500
Inj—10 |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
