Monograph Details
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Central Nervous System
> Anxiety/OCD
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LIBRIUM |
| Manufacturer |
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Valeant Pharmaceuticals, Inc |
| Legal Classification |
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CIV |
| Pharmacological Class |
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Benzodiazepine. |
| Generic Name |
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Chlordiazepoxide HCl 5mg, 10mg, 25mg; caps. |
| Also |
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• LIBRIUM INJECTABLE
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| Indications |
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Anxiety. |
| Children |
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<6yrs: not recommended. >6yrs: 5mg 2–4 times daily. May increase to 10mg 2–3 times daily. |
| Adults |
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Mild to moderate: 5–10mg 3–4 times daily. Severe: 20–25mg 3–4 times daily. Elderly or debilitated: 5mg 2–4 times daily. |
| Precautions |
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Drug or alcohol abuse. Suicidal tendencies. Depression. Renal or hepatic disease. Therapy for >4 months. Porphyria. Psychosis. Epilepsy. Change dose gradually. Monitor blood counts and liver function. Elderly. Debilitated. Pregnancy, nursing mothers: not recommended. |
| Interactions |
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Potentiates CNS depression with alcohol, other CNS depressants. Variable effects with anticoagulants. Avoid other psychotropics. |
| Adverse Reactions |
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Drowsiness, CNS depression, ataxia, confusion, paradoxical excitement, memory impairment, blood dyscrasias, jaundice, rash, edema, extrapyramidal effects, abuse potential. |
| How Supplied |
Caps 5mg—100
10mg, 25mg—100, 500
Inj—10 |
| Additional Resources |
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• Related Prescribing Note |
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