Monograph Details
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Cardiovascular System
> Hypertension
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SECTRAL |
| Manufacturer |
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Dr. Reddy's Laboratories, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Cardioselective β-blocker. |
| Generic Name |
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Acebutolol (as HCl) 200mg, 400mg; caps. |
| Indications |
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Hypertension. |
| Children |
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Not recommended. |
| Adults |
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Initially 400mg daily in 1–2 divided doses. Usual range: 200–800mg daily; max 1.2g/day in 2 divided doses. |
| Elderly |
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Max 800mg/day. |
| Contraindications |
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Severe bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock. |
| Precautions |
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Bronchospastic disease. Ischemic heart disease or failure. Renal or hepatic dysfunction. Diabetes. Hyperthyroidism. Vascular insufficiency. Surgery. Avoid abrupt cessation. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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May potentiate hypotension with prazosin, reserpine, other catecholamine-depleting drugs. Antagonized by NSAIDs. May increase cardiac effects of verapamil, digitalis. Avoid α-adrenergic agonists. May block epinephrine. |
| Adverse Reactions |
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Fatigue, dizziness, headache, GI upset, dyspnea, dysuria, insomnia, rash, myalgia, rhinitis, abnormal vision, hypotension, bradycardia, heart failure or block, bronchospasm, elevated ANA titers. |
| How Supplied |
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Caps—100 |
| Additional Resources |
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• Related Prescribing Note |
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