Monograph Details

Cardiovascular System > Hypertension
DEMADEX INJECTION
Manufacturer
Roche Laboratories
Legal Classification
Rx
Pharmacological Class
Diuretic (loop).
Generic Name
Torsemide 10mg/mL; for IV injection.
Also
DEMADEX
Indications
Hypertension.
Children
Not recommended.
Adults
5mg once daily, may increase to 10mg once daily. Give IV dose over a period of 2 minutes.
Contraindications
Anuria. Sulfonamide allergy.
Precautions
Hepatic disease with cirrhosis and ascites. Monitor electrolytes, BUN, creatinine, uric acid, and fluids. Pregnancy (Cat.B). Nursing mothers.
Interactions
Lithium and salicylate toxicity. Caution with NSAIDs. Antagonized by probenecid and indomethacin. Give oral dose 2 hours before or 4 hours after cholestyramine. Ototoxicity with aminoglycosides and ethacrynic acid.
Adverse Reactions
Dizziness, headache, nausea, weakness, vomiting, hyperglycemia, excessive urination, hyperuricemia, hypokalemia, excessive thirst, hypovolemia, impotence, esophageal hemorrhage, dyspepsia.
How Supplied
Tabs—100
Ampules—2mL, 5mL
Additional Resources
Related Prescribing Note