Monograph Details
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Cardiovascular System
> Hyperlipoproteinemias
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COLESTID |
| Manufacturer |
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Pfizer Labs |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Bile acid sequestrant. |
| Generic Name |
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Colestipol HCl 5g/pkt or scoop; granules; orange flavor (contains aspartame) or unflavored. |
| Also |
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• COLESTID TABLETS
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| Indications |
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Adjunct to diet to lower elevated serum total-C and LDL-C in primary hypercholesterolemia. |
| Children |
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Not recommended. |
| Adults |
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5g–30g daily once or in divided doses mixed with liquid. |
| Precautions |
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Obtain baseline serum cholesterol, LDL-C, and triglycerides, and monitor during therapy. May need Vit. A, D and K supplementation with long-term therapy. Exclude secondary causes of hypercholesterolemia (e.g., hypothyroidism, diabetes, nephrotic syndrome, dysproteinemias, obstructive liver disease, alcoholism). Constipation. Hemorrhoids. Pregnancy. Nursing mothers. |
| Interactions |
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Reduces absorption of thiazides, furosemide, tetracycline, penicillin G, gemfibrozil, others; monitor digitalis, propranolol; give other drugs at least 1 hour before or 4 hours after. |
| Adverse Reactions |
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Constipation, fecal impaction, aggravated hemorrhoids, GI upset, Vit. A, D, K deficiencies with prolonged use. |
| How Supplied |
Unflavored 5g pkt—30, 90
Bulk—300g, 500g (w. scoop)
Flavored 7.5g pkt—60
Bulk—450g
Tabs—120 |
| Additional Resources |
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• Related Prescribing Note |
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