Monograph Details
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Cardiovascular System
> Edema
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LASIX |
| Manufacturer |
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Sanofi Aventis |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Loop. |
| Generic Name |
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Furosemide 20mg, 40mg+, 80mg; tabs; +scored. |
| Indications |
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Edema. |
| Children |
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Initially 2mg/kg. Increase if needed by 1–2mg/kg after 6–8 hours; max 6mg/kg per day. Maintenance: lowest effective dose. |
| Adults |
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Initially 20–80mg daily. May repeat or increase after 6–8 hours; max 600mg/day. Maintenance: intermittent dosing optimal. |
| Contraindications |
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Anuria. Hepatic coma. Electrolyte depletion. |
| Precautions |
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Renal or hepatic dysfunction. Diabetes. Gout. SLE. Sulfonamide sensitivity. Monitor BP, electrolytes, fluids, blood, BUN. Potassium supplementation may be needed. Discontinue if progressive renal dysfunction occurs. Elderly. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Digitalis, lithium toxicity. Alcohol, CNS depressants may increase orthostatic hypotension. Antagonized by indomethacin. May alter excretion of salicylates, lithium. Hypokalemia with corticosteroids, ACTH. Antagonizes tubocurarine. Potentiates antihypertensives, succinylcholine. Ototoxicity with aminoglycosides, ethacrynic acid. |
| Adverse Reactions |
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Excessive diuresis, fluid or electrolyte imbalance, GI upset, dizziness, vertigo, paresthesias, orthostatic hypotension, hyperglycemia, jaundice, hyperuricemia, rash, photosensitivity, tinnitus, hearing loss, blood dyscrasias, renal calcification in premature infants. |
| How Supplied |
Tabs 20mg—100, 1000
40mg—100, 500, 1000
80mg—50, 500 |
| Additional Resources |
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• Related Prescribing Note |
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