Monograph Details
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Cardiovascular System
> Edema
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Indapamide |
| Manufacturer |
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Various generic manufacturers |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Diuretic (indoline). |
| Generic Name |
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Indapamide 1.25mg; tabs. |
| Indications |
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Edema. |
| Children |
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Not recommended. |
| Adults |
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Initially 2.5mg once daily in the AM. After 1wk, may increase to 5mg daily. |
| Contraindications |
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Anuria. Sulfonamide allergy. |
| Precautions |
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Renal or hepatic impairment. Arrhythmia. Diabetes. Gout. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, uric acid, glucose, and renal function. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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Digitalis, lithium toxicity. Adjust antidiabetic medications. NSAIDs may cause renal failure. ACTH, corticosteroids, amphotericin B increase hypokalemia risk. Hyperglycemia, hyperuricemia with diazoxide. Potentiates antihypertensives. May block epinephrine. May interfere with parathyroid tests. |
| Adverse Reactions |
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Electrolyte disorders (esp. hypokalemia, hyponatremia), hyperglycemia, hyperuricemia, gout, arrhythmias, headache, nervousness, blurred vision, muscle cramps, dizziness, fatigue, orthostatic hypotension, cough, GI disturbances. |
| How Supplied |
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Contact supplier. |
| Additional Resources |
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• Related Prescribing Note |
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